Type 1 hypersensitivity reaction pdf files

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1. Type I Hypersensitivity (Anaphylaxis): This type of hypersensitivity is the most common among all the types. About 17% of the human population may be affected, probably due to a natural proneness controlled by the genetic make-up. A symptomatic reaction only occurs in sensitized individuals, i.e., they must have had at least one prior asymptomatic contact with the offending antigen . Hypersensitivity reactions are commonly classified into four types. Type I hypersensitivity reactions are immediate allergic reactions (e.g., food and pollen allergies , asthma , anaphylaxis ). Atopy : Describes individuals that produce IgE Ab in response to various environmental Ag and develop immediate hypersensitivity (Type I) responses .(Asthma, eczema, hay fever, and urticaria) These individuals normally have a strong family history (autosomal transmission of atopy) 191/1/2014 Prof. Muhammad Akram Hossain, Hypersensitivity-1 Atopy Type I hypersensitivity (allergy) Augustine raj Introduction to Hypersensitivity & Allergy Dr Alok Tripathi Allergy Sadya Laraib Hypersensitivity The Microbiology Meducator HYPERSENSITIVITY abrishiya hypersensitivity type 1 MirzaNaadir Hypersensitivity dr. agale Shubhangi Agale Hypersensitivity oral and maxillofacial pathology Hypersensitivity There are two stages in the course of Type I hypersensitivity: immediate reaction and late-phase reaction. During the initial phase, there is a sudden response within minutes of exposure to the allergen. While the late-phase may develop 4 to 12 hours post early phase reaction and can last for up to 24 to 73 hours. Hypersensitivity Reactions - View presentation slides online. Ppt. Open navigation menu of hypersensitivity reactions has increased, especially in patients with cancer.2 Four basic types of hypersensitivity responses may occur (Table 1). Table 1 Types of Hypersensitivity Reactions Hypersensitivity reaction Definition Example(s) Timing Type I • IgE mediated (immediate) • Anaphylaxis • Minutes to generally within 1 this type may occur as systemic or local reaction: A)systemic reactions:skinerythema,followed by respiratory difficulty duo to bronchial constriction. B)local reactions:generally on skin ormucosal surface at site of Ag exposure. Allergy to penicillin, Aspergillusspores, rupture of Echinococcuscyst… in this typeAbare formed against Type I hypersensitivity (or immediate hypersensitivity) is an allergic reaction provoked by re-exposure to a specific type of antigen referred to as an allergen. [1] Type I is distinct from type II, type III and type IV hypersensitivities. Exposure may be by ingestion, inhalation, injection, or direct contact. Contents 1 Pathophysiology 3. Type I hypersensitivity is also known as immediate or anaphylactic hypersensitivity. The reaction may involve skin (urticariaand eczema), eyes (conjunctivitis), nasopharynx (rhinorrhea, rhinitis), bronchopulmonary tissues (asthma) and gastrointestinal tract (gastroenteritis). Granulomatous hypersensitivity reactions develop over a period of 21-28 days; the granulomas are formed by the aggr